NEURL2 Antikörper (N-Term)

Produktnummer ABIN2784965

Produktdetails anti-NEURL2 Antikörper

Target: NEURL2 (Neuralized Homolog 2 (NEURL2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Kaninchen, Rind (Kuh), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NEURL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MAAASEPVDS GALWGLERPE PPPTRFHRVH GANIRVDPSG TRATRVESFA

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against NEURL2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NEURL2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 285 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NEURL2

Target: NEURL2 (Neuralized Homolog 2 (NEURL2))

Andere Bezeichnung: NEURL2 (NEURL2 Produkte)

Synonyme: C20orf163 antikoerper, OZZ antikoerper, OZZ-E3 antikoerper, Neur2 antikoerper, Ozz antikoerper, Ozz-E3 antikoerper, neuralized E3 ubiquitin protein ligase 2 antikoerper, NEURL2 antikoerper, Neurl2 antikoerper

Hintergrund: NEURL2 contains 1 NHR (neuralized homology repeat) domain and 1 SOCS box domain. NEURL2 plays an important role in the process of myofiber differentiation and maturation. NEURL2 is the probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. NEURL2 probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, it controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma.
Alias Symbols: C20orf163, MGC125934, MGC125935, OZZ, Ozz-E3
Protein Interaction Partner: CTNNB1,
Protein Size: 285

Molekulargewicht: 32 kDa

Gen-ID: 140825

NCBI Accession: NM_080749, NP_542787

UniProt: Q9BR09