GLMN Antikörper (N-Term)

Produktnummer ABIN406218

Produktdetails anti-GLMN Antikörper

Target: GLMN (Glomulin, FKBP Associated Protein (GLMN))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLMN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AVEELQSIIK RCQILEEQDF KEEDFGLFQL AGQRCIEEGH TDQLLEIIQN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GLMN. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GLMN

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 594 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GLMN

Target: GLMN (Glomulin, FKBP Associated Protein (GLMN))

Andere Bezeichnung: GLMN (GLMN Produkte)

Hintergrund: GLMN is a phosphorylated protein that is a member of a Skp1-Cullin-F-box-like complex. The protein is essential for normal development of the vasculature and mutations in this gene have been associated with glomuvenous malformations, also called glomangiomas. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.This gene encodes a phosphorylated protein that is a member of a Skp1-Cullin-F-box-like complex. The protein is essential for normal development of the vasculature and mutations in this gene have been associated with glomuvenous malformations, also called glomangiomas. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FAP, FAP48, FAP68, FKBPAP, GLML, GVM, VMGLOM
Protein Interaction Partner: UBC, CDC37L1, CDC37, FKBP5, FKBP4, SAV1, FBXW7, RBX1, RNF7, CUL1, SKP1, EIF3A, CUL2, CUL3, CUL4A, TMEM173, NSFL1C, FKBP1A, MET,
Protein Size: 594

Molekulargewicht: 68 kDa

Gen-ID: 11146

NCBI Accession: NM_053274, NP_444504

UniProt: Q92990

Pathways: Tube Formation