TSEN15 Antikörper (C-Term)

Produktnummer ABIN2784943

Der Kaninchen Polyklonal anti-TSEN15 Antikörper wird verwendet zum Nachweis von TSEN15 in Proben von Human, Maus, Rind (Kuh), Hund, Schwein, Ratte, Meerschweinchen und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für TSEN15 Antikörper (C-Term) (ABIN2784943)

Target: TSEN15 (tRNA Splicing Endonuclease 15 Homolog (TSEN15))

Reaktivität: Human, Maus, Rind (Kuh), Hund, Schwein, Ratte, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TSEN15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TSEN15 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Tsen15 Antibody - C-terminal region

Sequenz: ASLSHNRIRE ILKASRKLQG DPELPMSFTL AIVESDSTIV YYKLTDGFML

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Tsen15. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52469-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu TSEN15

Target: TSEN15 (tRNA Splicing Endonuclease 15 Homolog (TSEN15))

Andere Bezeichnung: Tsen15

Hintergrund:

Targeted Subunit: Sen15

Background Information: Tsen15 is a non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3' end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3' end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events.

Gene Name: TRNA splicing endonuclease 15 homolog (S. cerevisiae)

Alternative Symbols: Sen15, AL023077, 5730449L18Rik

Protein Name: tRNA-splicing endonuclease subunit Sen15

Molekulargewicht: 18kDa

Gen-ID: 66637

NCBI Accession: NP_079953

UniProt: Q8R3W5