MED8 Antikörper (N-Term)

Produktnummer ABIN406216

Produktdetails anti-MED8 Antikörper

Target: MED8 (Mediator Complex Subunit 8 (MED8))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MED8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MQREEKQLEA SLDALLSQVA DLKNSLGSFI CKLENEYGRL TWPSVLDSFA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against MED8. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MED8

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 301 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MED8

Target: MED8 (Mediator Complex Subunit 8 (MED8))

Andere Bezeichnung: MED8 (MED8 Produkte)

Hintergrund: MED8 is a protein that is one of more than 20 subunits of the mediator complex, first identified in S. cerevisiae, that is required for activation of transcription. MED8 also interacts with elongins B and C, and CUL2 and RBX1, to reconstitute a ubiquitin ligase.This gene encodes a protein that is one of more than 20 subunits of the mediator complex, first identified in S. cerevisiae, that is required for activation of transcription. The product of this gene also interacts with elongins B and C, and CUL2 and RBX1, to reconstitute a ubiquitin ligase. Two alternative transcripts encoding different isoforms have been described.
Alias Symbols: ARC32, MGC17544, MGC19641
Protein Interaction Partner: PNMA1, KRT40, CDK19, CDK8, MED19, MED26, FBXW7, EPAS1, MED29, MED18, CPSF1, MED4, MED16, MED12, MED24, MED21, MED14, MED1, HIST1H1E, APP, MED11, SUMO2, MED10, RBX1, CTDP1, CUL2, TCEB2, TCEB1, MED28, OBFC1, ZC3H13, TRIP4, TADA2A, THOC7, PHYHIP, MED20, MED9
Protein Size: 301

Molekulargewicht: 33 kDa

Gen-ID: 112950

NCBI Accession: NM_052877, NP_443109

Pathways: Regulation of Lipid Metabolism by PPARalpha