MED8 Antikörper (N-Term)

Produktnummer ABIN2784933

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MED8 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio) und Kaninchen.

Kurzübersicht für MED8 Antikörper (N-Term) (ABIN2784933)

Target: MED8 (Mediator Complex Subunit 8 (MED8))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MED8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MED8 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: MED8 Antibody - N-terminal region

Sequenz: MQREEKQLEA SLDALLSQVA DLKNSLGSFI CKLENEYGRL TWPSVLDSFA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against MED8. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MED8

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52440-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu MED8

Target: MED8 (Mediator Complex Subunit 8 (MED8))

Andere Bezeichnung: MED8

Hintergrund:

Targeted Subunit: 8

Background Information: MED8 is a protein that is one of more than 20 subunits of the mediator complex, first identified in S. cerevisiae, that is required for activation of transcription. MED8 also interacts with elongins B and C, and CUL2 and RBX1, to reconstitute a ubiquitin ligase.This gene encodes a protein that is one of more than 20 subunits of the mediator complex, first identified in S. cerevisiae, that is required for activation of transcription. The product of this gene also interacts with elongins B and C, and CUL2 and RBX1, to reconstitute a ubiquitin ligase. Two alternative transcripts encoding different isoforms have been described.

Gene Name: Mediator complex subunit 8

Alternative Symbols: ARC32

Protein Name: Mediator of RNA polymerase II transcription subunit 8

Molekulargewicht: 33kDa

Gen-ID: 112950

NCBI Accession: NP_443109

UniProt: Q96G25

Pathways: Regulation of Lipid Metabolism by PPARalpha