CSH1 Antikörper (Middle Region)

Produktnummer ABIN2784912

Produktdetails anti-CSH1 Antikörper

Target: CSH1 (Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Hund, Meerschweinchen, Kaninchen, Ratte, Rind (Kuh), Ziege, Pferd, Schwein, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CSH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LFDHAMLQAH RAHQLAIDTY QEFRLEDGSR RTGQILKQTY SKFDTNSHNH

Homologie: Cow: 79%, Dog: 86%, Goat: 90%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 79%, Rat: 86%, Sheep: 90%

Produktmerkmale: This is a rabbit polyclonal antibody against CSH2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CSH2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 122 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CSH1

Target: CSH1 (Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1))

Andere Bezeichnung: CSH2 (CSH1 Produkte)

Hintergrund: The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation, an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, while the ratio of 1 to 2 increases by term. Structural and expression differences provide avenues for developmental regulation and tissue specificity.
Alias Symbols: CS-2, CSB, hCS-B
Protein Interaction Partner: PTPN12, SMAD9, SMAD4, SMAD3, SMAD2, POLR2A,
Protein Size: 122

Molekulargewicht: 14 kDa

Gen-ID: 1443

NCBI Accession: NM_022645, NP_072171

UniProt: B1A4H9

Pathways: Response to Growth Hormone Stimulus