NUP50 Antikörper (C-Term)

Produktnummer ABIN2784862

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch NUP50 in WB und IF. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen, Schwein und Saccharomyces cerevisiae.

Kurzübersicht für NUP50 Antikörper (C-Term) (ABIN2784862)

Target: NUP50 (Nucleoporin 50kDa (NUP50))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen, Schwein, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUP50 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-NUP50 Antikörper

Bindungsspezifität: C-Term

Sequenz: TTQSKPVSSP FPTKPLEGQA EGDSGECKGG DEEENDEPPK VVVTEVKEED

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 91%, Pig: 100%, Rabbit: 100%, Rat: 92%, Yeast: 80%

Produktmerkmale: This is a rabbit polyclonal antibody against NUP50. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NUP50

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 468 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NUP50

Target: NUP50 (Nucleoporin 50kDa (NUP50))

Andere Bezeichnung: NUP50

Hintergrund: The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. NUP50 is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import.The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: MGC39961, NPAP60, NPAP60L
Protein Interaction Partner: KPNA5, KPNA4, KPNA3, KPNA2, KPNA1, KPNA6, UBC, KIAA1033, SART3, TTI1, TSC22D1, IKBKAP, KIF5B, EPB41L1, ACACA, SRPK2, LMNA, HDAC6, NPM1, UBAP2, TOR1AIP1, NUP153, APP, CUL3, Mki67, Kifc5b, SLX4, KPNB1, XPO1, RAN, CDKN1B, IPO13,
Protein Size: 468

Molekulargewicht: 50 kDa

Gen-ID: 10762

NCBI Accession: NM_007172, NP_009103

UniProt: Q9UKX7

Pathways: Tube Formation