KATNA1 Antikörper (C-Term)
Kurzübersicht für KATNA1 Antikörper (C-Term) (ABIN2784857)
Target
Alle KATNA1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- Katna1 Antibody - C-terminal region
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Sequenz
- DDPSKMVMVL AATNFPWDID EALRRRLEKR IYIPLPSAKG REELLRISLR
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
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Produktmerkmale
- This is a rabbit polyclonal antibody against Katna1. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide corresponding to a region of Mouse
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52277-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- KATNA1 (Katanin P60 (ATPase Containing) Subunit A 1 (KATNA1))
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Andere Bezeichnung
- Katna1
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Hintergrund
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Targeted Subunit: A1
Background Information: Katna1 severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays, such as that seen during disassembly of interphase microtubules at the G2-M transition.It may also be required for microtubule release from the centrosome after nucleation. In mitotic spindles this could allow depolymerization of the microtubule end proximal to the centrosome, and subsequent poleward microtubule flux. In neurons, microtubule release within the cell body allows their subsequent transport into neuronal processes by microtubule dependent motor proteins. This transport is required for axonal growth.
Gene Name: Katanin p60 (ATPase-containing) subunit A1
Alternative Symbols: -
Protein Name: Katanin p60 ATPase-containing subunit A1
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Molekulargewicht
- 54kDa
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Gen-ID
- 23924
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NCBI Accession
- NP_035965
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UniProt
- Q9WV86
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Pathways
- Microtubule Dynamics
Target
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