KATNA1 Antikörper (C-Term)

Produktnummer ABIN2784857

Produktdetails anti-KATNA1 Antikörper

Target: KATNA1 (Katanin P60 (ATPase Containing) Subunit A 1 (KATNA1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KATNA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: DDPSKMVMVL AATNFPWDID EALRRRLEKR IYIPLPSAKG REELLRISLR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against Katna1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 491 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu KATNA1

Target: KATNA1 (Katanin P60 (ATPase Containing) Subunit A 1 (KATNA1))

Andere Bezeichnung: Katna1 (KATNA1 Produkte)

Hintergrund: Katna1 severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays, such as that seen during disassembly of interphase microtubules at the G2-M transition.It may also be required for microtubule release from the centrosome after nucleation. In mitotic spindles this could allow depolymerization of the microtubule end proximal to the centrosome, and subsequent poleward microtubule flux. In neurons, microtubule release within the cell body allows their subsequent transport into neuronal processes by microtubule dependent motor proteins. This transport is required for axonal growth.
Alias Symbols: -
Protein Interaction Partner: KATNB1,
Protein Size: 491

Molekulargewicht: 54 kDa

Gen-ID: 23924

NCBI Accession: NM_011835, NP_035965

UniProt: Q9WV86

Pathways: Microtubule Dynamics