RALBP1 Antikörper (N-Term)

Produktnummer ABIN2784844

Der Kaninchen Polyklonal anti-RALBP1 Antikörper (ABIN2784844) detektiert spezifisch RALBP1 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Rind (Kuh), Ziege, Pferd, Schwein, Kaninchen und Meerschweinchen.

Kurzübersicht für RALBP1 Antikörper (N-Term) (ABIN2784844)

Target: RALBP1 (RalA Binding Protein 1 (RALBP1))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Ziege, Pferd, Schwein, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RALBP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-RALBP1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: RALBP1 Antibody - N-terminal region

Sequenz: MTECFLPPTS SPSEHRRVEH GSGLTRTPSS EEISPTKFPG LYRTGEPSPP

Homologie: Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RALBP1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RALBP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52251-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu RALBP1

Target: RALBP1 (RalA Binding Protein 1 (RALBP1))

Andere Bezeichnung: RALBP1

Hintergrund:

Background Information: RALBP1 can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. RALBP1 mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes.RALBP1 can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. RALBP1 serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.

Gene Name: RalA binding protein 1

Alternative Symbols: RIP1, RLIP1, RLIP76

Protein Name: RalA-binding protein 1

Molekulargewicht: 76kDa

Gen-ID: 10928

NCBI Accession: NP_006779

UniProt: Q15311