RALBP1 Antikörper (N-Term)

Produktnummer ABIN2784844

Dieser Anti-RALBP1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von RALBP1 in WB und IHC. Geeignet für Human, Maus, Ratte, Hund, Rind (Kuh), Ziege, Pferd, Schwein, Kaninchen und Meerschweinchen.

Kurzübersicht für RALBP1 Antikörper (N-Term) (ABIN2784844)

Target: RALBP1 (RalA Binding Protein 1 (RALBP1))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Ziege, Pferd, Schwein, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RALBP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-RALBP1 Antikörper

Bindungsspezifität: N-Term

Sequenz: MTECFLPPTS SPSEHRRVEH GSGLTRTPSS EEISPTKFPG LYRTGEPSPP

Homologie: Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RALBP1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RALBP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 655 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RALBP1

Target: RALBP1 (RalA Binding Protein 1 (RALBP1))

Andere Bezeichnung: RALBP1

Hintergrund: RALBP1 can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. RALBP1 mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes.RALBP1 can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. RALBP1 serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.
Alias Symbols: RIP, RIP1, RLIP76, RLIP1
Protein Interaction Partner: TNIP1, CEP57, SMARCE1, PPL, GPS2, GSE1, ZNF707, ZBTB38, C1orf216, TBRG1, AMOTL2, TFPT, UBC, RALB, GPSM1, PRKCA, CPSF2, POLR2A, AP2A1, SYNJ2BP, HOOK2, REPS1, FADD, RAC1, TRAF2, CASP8, AP2M1, REPS2, IKBKG, RALA, CCNB1, HSP90AA1, HSF1, EPN1, NUMB, GTF3A, TNF
Protein Size: 655

Molekulargewicht: 76 kDa

Gen-ID: 10928

NCBI Accession: NM_006788, NP_006779

UniProt: Q15311