FGL2 Antikörper (Middle Region)

Produktnummer ABIN2784837

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FGL2 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Pferd, Schwein, Rind (Kuh), Meerschweinchen und Kaninchen und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für FGL2 Antikörper (Middle Region) (ABIN2784837)

Target: FGL2 (Fibrinogen-Like 2 (FGL2))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Schwein, Rind (Kuh), Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FGL2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: WTVLQARLDG STNFTRTWQD YKAGFGNLRR EFWLGNDKIH LLTKSKEMIL

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FGL2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FGL2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 439 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-FGL2 Antikörper (ABIN2784837)

Pischke, Gustavsen, Orrem, Egge, Courivaud, Fontenelle, Despont, Bongoni, Rieben, Tønnessen, Nunn, Scott, Skulstad, Barratt-Due, Mollnes: "Complement factor 5 blockade reduces porcine myocardial infarction size and improves immediate cardiac function." in: Basic research in cardiology, Vol. 112, Issue 3, pp. 20, (2017) (PubMed).

Bongoni, Klymiuk, Wolf, Ayares, Rieben, Cowan: "Transgenic Expression of Human Thrombomodulin Inhibits HMGB1-Induced Porcine Aortic Endothelial Cell Activation." in: Transplantation, Vol. 100, Issue 9, pp. 1871-9, (2016) (PubMed).

Details zu FGL2

Target: FGL2 (Fibrinogen-Like 2 (FGL2))

Andere Bezeichnung: FGL2

Hintergrund: The protein encoded by this gene is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. This protein may play a role in physiologic functions at mucosal sites.
Alias Symbols: T49, pT49
Protein Size: 439

Molekulargewicht: 48 kDa

Gen-ID: 10875

NCBI Accession: NM_006682, NP_006673

UniProt: Q14314