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DLC1 Antikörper (C-Term)

DLC1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2784792
  • Target Alle DLC1 Antikörper anzeigen
    DLC1 (Deleted in Liver Cancer 1 (DLC1))
    Bindungsspezifität
    • 15
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 38
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)
    Wirt
    • 35
    • 4
    • 1
    Kaninchen
    Klonalität
    • 38
    • 2
    Polyklonal
    Konjugat
    • 19
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DLC1 Antikörper ist unkonjugiert
    Applikation
    • 13
    • 13
    • 11
    • 10
    • 9
    • 8
    • 6
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequenz
    NLAVCLAPSL FHLNTLKREN SSPRVMQRKQ SLGKPDQKDL NENLAATQGL
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%
    Produktmerkmale
    This is a rabbit polyclonal antibody against DLC1. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human DLC1
    Top Product
    Discover our top product DLC1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 467 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    DLC1 (Deleted in Liver Cancer 1 (DLC1))
    Andere Bezeichnung
    DLC1 (DLC1 Produkte)
    Synonyme
    ARHGAP7 antikoerper, HP antikoerper, STARD12 antikoerper, p122-RhoGAP antikoerper, rhogap7 antikoerper, DLC-1 antikoerper, StARD12 antikoerper, Dlc-1 antikoerper, A730069N07Rik antikoerper, Arhgap7 antikoerper, dlc-1 antikoerper, RhoGAP antikoerper, Dlc1 antikoerper, DLC1 Rho GTPase activating protein antikoerper, DLC1 Rho GTPase activating protein S homeolog antikoerper, rho GTPase-activating protein 7 antikoerper, deleted in liver cancer 1 antikoerper, DLC1 antikoerper, dlc1.S antikoerper, dlc1 antikoerper, LOC100456847 antikoerper, Dlc1 antikoerper, LOC100729904 antikoerper
    Hintergrund
    This gene is deleted in the primary tumor of hepatocellular carcinoma. It maps to 8p22-p21.3, a region frequently deleted in solid tumors. It is suggested that this gene is a candidate tumor suppressor gene for human liver cancer, as well as for prostate, lung, colorectal, and breast cancers. DLC1 functions as a GTPase-activating protein specific for Rho and an activator of PLCD1 in vivo and induces morphological changes and detachment through cytoskeletal reorganization.
    Alias Symbols: ARHGAP7, FLJ21120, HP, STARD12, p122-RhoGAP
    Protein Interaction Partner: DDB1, FBXW5, CUL1, CUL2, CUL3, CUL4A, UBC, TENC1, CAV1, S100A10, WWC1, AKT1,
    Protein Size: 467
    Molekulargewicht
    52 kDa
    Gen-ID
    10395
    NCBI Accession
    NM_001164271
    UniProt
    Q9Y238
    Pathways
    Tube Formation, Positive Regulation of Endopeptidase Activity
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