ACTR1B Antikörper (C-Term)

Produktnummer ABIN2784773

Dieser Anti-ACTR1B Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von ACTR1B in WB. Geeignet für Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd und Zebrafisch (Danio rerio). Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für ACTR1B Antikörper (C-Term) (ABIN2784773)

Target: ACTR1B (ARP1 Actin-Related Protein 1 Homolog B, Centractin beta (ACTR1B))

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACTR1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ACTR1B Antikörper

Bindungsspezifität: C-Term

Sequenz: KIKISAPQER LYSTWIGGSI LASLDTFKKM WVSKKEYEED GSRAIHRKTF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against ACTR1B. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ACTR1B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 376 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ACTR1B Antikörper (ABIN2784773)

Hwang, Weng, Lin, Bau, Ko, Tsai, Tsai, Wu, Lin, Huang, Kuo: "Hypoxia-induced compensatory effect as related to Shh and HIF-1alpha in ischemia embryo rat heart." in: Molecular and cellular biochemistry, Vol. 311, Issue 1-2, pp. 179-87, (2008) (PubMed).

Details zu ACTR1B

Target: ACTR1B (ARP1 Actin-Related Protein 1 Homolog B, Centractin beta (ACTR1B))

Andere Bezeichnung: ACTR1B

Hintergrund: ACTR1B is a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. ACTR1B, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90 % amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex.This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins are of equal length and share 90 % amino acid identity. They are present in a constant ratio of approximately 1:15 in the dynactin complex.
Alias Symbols: ARP1B, CTRN2, PC3
Protein Interaction Partner: SEH1L, ACTR10, DCTN4, DCTN2, ACTR1A, RABEP1, LMNB1, DCTN3, APP, SMAD6, CUL3, UBC, TK1, MAPK6, CSNK2B, Dctn1, Capza1, CHD3, ACTA1,
Protein Size: 376

Molekulargewicht: 42 kDa

Gen-ID: 10120

NCBI Accession: NM_005735, NP_005726

UniProt: P42025