SAE1 Antikörper (N-Term)

Produktnummer ABIN2784763

Produktdetails anti-SAE1 Antikörper

Target: SAE1 (SUMO1 Activating Enzyme Subunit 1 (SAE1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SAE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MVEKEEAGGG ISEEEAAQYD RQIRLWGLEA QKRLRASRVL LVGLKGLGAE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%, Yeast: 86%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SAE1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SAE1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 346 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SAE1

Target: SAE1 (SUMO1 Activating Enzyme Subunit 1 (SAE1))

Andere Bezeichnung: SAE1 (SAE1 Produkte)

Synonyme: AOS1 antikoerper, HSPC140 antikoerper, SUA1 antikoerper, UBLE1A antikoerper, 2400010M20Rik antikoerper, 2610044L12Rik antikoerper, AL033372 antikoerper, AW743391 antikoerper, D7Ertd177e antikoerper, Sua1 antikoerper, Uble1a antikoerper, Aos1p antikoerper, Sua1p antikoerper, aos antikoerper, sae2a antikoerper, uble1a antikoerper, wu:fa28b04 antikoerper, zgc:86633 antikoerper, SUMO1 activating enzyme subunit 1 antikoerper, SUMO1 activating enzyme subunit 1 L homeolog antikoerper, SAE1 antikoerper, Sae1 antikoerper, sae1.L antikoerper, sae1 antikoerper

Hintergrund: Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1, MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).
Alias Symbols: AOS1, FLJ3091, HSPC140, SUA1, UBLE1A
Protein Interaction Partner: FUS, USP39, SUMO2, HSPA2, HSPA1A, UBC, TRMT10A, DPP9, RPRD1B, NPLOC4, OSGEP, PANK4, WDR4, CUL5, TPD52L2, SRP14, RANGAP1, PPP2R5E, MCM3, LPP, DHPS, CALU, ADSL, AARS, PDE12, TP53RK, UBE2I, UBA2, BAG3, PTK2, IL3RA, APP, SUMO1, ETV4, BCL6, UBE2E3, SUMO3, SP10
Protein Size: 346

Molekulargewicht: 38 kDa

Gen-ID: 10055

NCBI Accession: NM_005500, NP_005491

UniProt: Q9UBE0