Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

CLK1 Antikörper (N-Term)

CLK1 Reaktivität: Human, Maus, Pferd, Kaninchen, Ratte, Rind (Kuh), Hund, Meerschweinchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2784736
  • Target Alle CLK1 Antikörper anzeigen
    CLK1 (CDC like Kinase 1 (CLK1))
    Bindungsspezifität
    • 14
    • 9
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 33
    • 27
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Pferd, Kaninchen, Ratte, Rind (Kuh), Hund, Meerschweinchen
    Wirt
    • 45
    • 2
    Kaninchen
    Klonalität
    • 47
    Polyklonal
    Konjugat
    • 20
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CLK1 Antikörper ist unkonjugiert
    Applikation
    • 39
    • 29
    • 9
    • 7
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequenz
    HSSAQENKRC KYNHSKMCDS HYLESRSINE KDYHSRRYID EYRNDYTQGC
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 85%
    Produktmerkmale
    This is a rabbit polyclonal antibody against CLK1. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human CLK1
    Top Product
    Discover our top product CLK1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 484 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Aubol, Wu, Keshwani, Movassat, Fattet, Hertel, Fu, Adams: "Release of SR Proteins from CLK1 by SRPK1: A Symbiotic Kinase System for Phosphorylation Control of Pre-mRNA Splicing." in: Molecular cell, Vol. 63, Issue 2, pp. 218-228, (2016) (PubMed).

    Eisenreich, Zakrzewicz, Huber, Thierbach, Pepke, Goldin-Lang, Schultheiss, Pries, Rauch: "Regulation of pro-angiogenic tissue factor expression in hypoxia-induced human lung cancer cells." in: Oncology reports, Vol. 30, Issue 1, pp. 462-70, (2013) (PubMed).

  • Target
    CLK1 (CDC like Kinase 1 (CLK1))
    Andere Bezeichnung
    CLK1 (CLK1 Produkte)
    Synonyme
    CLK antikoerper, CLK/STY antikoerper, STY antikoerper, CDC like kinase 1 antikoerper, CDC-like kinase 1 antikoerper, CLK1 antikoerper, Clk1 antikoerper
    Hintergrund
    This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: CLK, CLK/STY, STY
    Protein Interaction Partner: KRTAP10-7, PDE9A, PRMT5, SRPK2, SRPK1, CLK1, BAG3, PIAS4, ISG15, UBC, YWHAG, LUC7L3, PPIG, SRSF6, PRPF4, GOLM1, UBL5, SRSF1, PTPN1, MBP, BCLAF1, NCOR1, SRSF3, SAFB,
    Protein Size: 484
    Molekulargewicht
    57 kDa
    Gen-ID
    1195
    NCBI Accession
    NM_004071, NP_004062
    UniProt
    P49759
Sie sind hier:
Kundenservice