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CENPB Antikörper (C-Term)

CENPB Reaktivität: Human, Maus, Ratte, Pferd, Schwein, Schaf, Rind (Kuh), Saccharomyces cerevisiae, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2784717
  • Target Alle CENPB Antikörper anzeigen
    CENPB (Centromere Protein B (CENPB))
    Bindungsspezifität
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    Human, Maus, Ratte, Pferd, Schwein, Schaf, Rind (Kuh), Saccharomyces cerevisiae, Zebrafisch (Danio rerio)
    Wirt
    • 16
    • 2
    Kaninchen
    Klonalität
    • 18
    Polyklonal
    Konjugat
    • 10
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CENPB Antikörper ist unkonjugiert
    Applikation
    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    GGEDSDSDSE EEDDEEEDDE DEDDDDDEED GDEVPVPSFG EAMAYFAMVK
    Homologie
    Cow: 83%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 86%, Rat: 100%, Sheep: 86%, Yeast: 100%, Zebrafish: 75%
    Produktmerkmale
    This is a rabbit polyclonal antibody against CENPB. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human CENPB
    Top Product
    Discover our top product CENPB Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 599 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CENPB (Centromere Protein B (CENPB))
    Andere Bezeichnung
    CENPB (CENPB Produkte)
    Synonyme
    CENPB antikoerper, CENP-B antikoerper, centromere protein B antikoerper, centromere protein B, 80kDa antikoerper, CENPB antikoerper, Cenpb antikoerper
    Hintergrund
    CENPB is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies.This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: -
    Protein Interaction Partner: UBC, RNF2, NR3C1, FBXO25, CENPA, APP, GFI1B, SUMO2, SMN1, PIN1, GSK3B, GADD45A, CSNK2B, CDKN1A, ANXA7, RPS6KA6, TK1, TAC1, TAF1D, PARP1, PARP2, HAND2, CENPB,
    Protein Size: 599
    Molekulargewicht
    65 kDa
    Gen-ID
    1059
    NCBI Accession
    NM_001810, NP_001801
    UniProt
    P07199
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