DPH1 Antikörper (Middle Region)

Produktnummer ABIN2784708

Der Kaninchen Polyklonal Anti-DPH1-Antikörper wurde für WB und IHC validiert. Er ist geeignet, DPH1 in Proben von Human, Maus, Hund, Meerschweinchen, Pferd, Kaninchen, Ratte, Rind (Kuh), Saccharomyces cerevisiae und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für DPH1 Antikörper (Middle Region) (ABIN2784708)

Target: DPH1 (DPH1 Homolog (DPH1))

Reaktivität: Human, Maus, Hund, Meerschweinchen, Pferd, Kaninchen, Ratte, Rind (Kuh), Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DPH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-DPH1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: RMQAARQEAI ATARSAKSWG LILGTLGRQG SPKILEHLES RLRALGLSFV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 83%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against DPH1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DPH1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 443 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DPH1

Target: DPH1 (DPH1 Homolog (DPH1))

Andere Bezeichnung: DPH1

Hintergrund: Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2, MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH1 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]). Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2, MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH1 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-40 AF321876.1 1-40 41-1028 BC003099.1 3-990 1029-1410 BP417755.1 78-459 1411-2188 AK090530.1 1484-2261 2189-2200 AF321876.1 2189-2200
Alias Symbols: DPH2L, DPH2L1, FLJ33211, OVCA1
Protein Interaction Partner: UBC, TFCP2, MMS19, UBD, TP63, TP73, TP53, RBM8A, HSPA5,
Protein Size: 443

Molekulargewicht: 49 kDa

Gen-ID: 1801

NCBI Accession: NM_001383, NP_001374

UniProt: Q9BZG8