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CHN2 Antikörper (N-Term)

CHN2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2784666
  • Target Alle CHN2 Antikörper anzeigen
    CHN2 (Chimerin (Chimaerin) 2 (CHN2))
    Bindungsspezifität
    • 7
    • 6
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 25
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)
    Wirt
    • 26
    • 1
    Kaninchen
    Klonalität
    • 27
    Polyklonal
    Konjugat
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    Dieser CHN2 Antikörper ist unkonjugiert
    Applikation
    • 21
    • 19
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    NHFNYEKTHN FKVHTFRGPH WCEYCANFMW GLIAQGVRCS DCGLNVHKQC
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against CHN2. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human CHN2
    Top Product
    Discover our top product CHN2 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 332 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CHN2 (Chimerin (Chimaerin) 2 (CHN2))
    Andere Bezeichnung
    CHN2 (CHN2 Produkte)
    Synonyme
    1700026N20Rik antikoerper, 4930557O16Rik antikoerper, ARHGAP3 antikoerper, Bch antikoerper, BCH antikoerper, CHN2-3 antikoerper, RHOGAP3 antikoerper, chimerin 2 antikoerper, chimerin 2 L homeolog antikoerper, chn2 antikoerper, CHN2 antikoerper, Chn2 antikoerper, chn2.L antikoerper
    Hintergrund
    CHN2 is a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. This protein has GTPase-activating protein activity that is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. CHN2 plays a role in the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors, and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men. This gene is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. This protein has GTPase-activating protein activity that is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. The protein plays a role in the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors, and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
    Alias Symbols: ARHGAP3, BCH, MGC138360, RHOGAP3, CHN2-3
    Protein Interaction Partner: ERBB3, RAC1, RACGAP1, TGFBR1, BAG6, AKT1,
    Protein Size: 332
    Molekulargewicht
    38 kDa
    Gen-ID
    1124
    NCBI Accession
    NM_001039936, NP_001035025
    UniProt
    P52757
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