RDM1 Antikörper (Middle Region)
Kurzübersicht für RDM1 Antikörper (Middle Region) (ABIN2784660)
Target
Alle RDM1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Verwendungszweck
- RDM1 Antibody - middle region
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Sequenz
- NSSKCQELAN YYFGFNGCSK RIIKLQELSD LEERENEDSM VPLPKQSLKF
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Homologie
- Cow: 83%, Dog: 93%, Guinea Pig: 91%, Human: 100%, Mouse: 83%, Pig: 93%, Rabbit: 93%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against RDM1. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human RDM1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51853-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- RDM1 (RAD52 Motif 1 (RDM1))
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Andere Bezeichnung
- RDM1
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Hintergrund
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Background Information: RDM1 is a protein involved in the cellular response to cisplatin, a drug commonly used in chemotherapy. It contains two motifs: a motif found in RAD52, a protein that functions in DNA double-strand breaks and homologous recombination, and an RNA recognition motif (RRM) that is not found in RAD52. The RAD52 motif region in RAD52 is important for protein function and may be involved in DNA binding or oligomerization.This gene encodes a protein involved in the cellular response to cisplatin, a drug commonly used in chemotherapy. The protein encoded by this gene contains two motifs: a motif found in RAD52, a protein that functions in DNA double-strand breaks and homologous recombination, and an RNA recognition motif (RRM) that is not found in RAD52. The RAD52 motif region in RAD52 is important for protein function and may be involved in DNA binding or oligomerization. Alternatively spliced transcript variants encoding different isoforms have been reported.
Gene Name: RAD52 motif 1
Alternative Symbols: RAD52B
Protein Name: RAD52 motif-containing protein 1 Ensembl ENSP00000378036
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Molekulargewicht
- 26kDa
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Gen-ID
- 201299
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NCBI Accession
- NP_001030008
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UniProt
- A8MY68
Target
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