ADA Antikörper (N-Term)

Produktnummer ABIN2784608

Produktdetails anti-ADA Antikörper

Target: ADA (Adenosine Deaminase (ADA))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AIAGCREAIK RIAYEFVEMK AKEGVVYVEV RYSPHLLANS KVEPIPWNQA

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ADA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ADA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 363 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ADA Antikörper (ABIN2784608)

Ferrante, Martire, Pepponi, Varani, Vincenzi, Ferraro, Beggiato, Tebano, Popoli: "Expression, pharmacology and functional activity of adenosine A1 receptors in genetic models of Huntington's disease." in: Neurobiology of disease, Vol. 71, pp. 193-204, (2014) (PubMed).

Details zu ADA

Target: ADA (Adenosine Deaminase (ADA))

Andere Bezeichnung: ADA (ADA Produkte)

Synonyme: ADA-like antikoerper, xada antikoerper, ADA antikoerper, CG11994 antikoerper, Dmel\\CG11994 antikoerper, DrosADA antikoerper, dADA antikoerper, zgc:92028 antikoerper, adenosine deaminase antikoerper, adenosine deaminase S homeolog antikoerper, Adenosine deaminase antikoerper, ADA antikoerper, Ada antikoerper, ada.S antikoerper, ada antikoerper

Hintergrund: ADA is an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia.
Alias Symbols: -
Protein Interaction Partner: UBC, SGCD, PIAS2, TERF2IP, TINF2, ADORA2B, DPP4, NR3C1, DRD1, GRB2, ADORA2A, ADORA1,
Protein Size: 363

Molekulargewicht: 41 kDa

Gen-ID: 100

NCBI Accession: NM_000022, NP_000013

UniProt: P00813

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Ribonucleoside Biosynthetic Process