ADA Antikörper (N-Term)

Produktnummer ABIN2784608

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-ADA Antikörper (ABIN2784608) detektiert spezifisch ADA in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Kaninchen, Pferd und Hund.

Kurzübersicht für ADA Antikörper (N-Term) (ABIN2784608)

Target: ADA (Adenosine Deaminase (ADA))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Kaninchen, Pferd, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ADA Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: ADA Antibody - N-terminal region

Sequenz: AIAGCREAIK RIAYEFVEMK AKEGVVYVEV RYSPHLLANS KVEPIPWNQA

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ADA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ADA

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51757-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ADA Antikörper (ABIN2784608)

Ferrante, Martire, Pepponi, Varani, Vincenzi, Ferraro, Beggiato, Tebano, Popoli: "Expression, pharmacology and functional activity of adenosine A1 receptors in genetic models of Huntington's disease." in: Neurobiology of disease, Vol. 71, pp. 193-204, (2014) (PubMed).

Details zu ADA

Target: ADA (Adenosine Deaminase (ADA))

Andere Bezeichnung: ADA

Hintergrund:

Background Information: ADA is an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia.

Gene Name: Adenosine deaminase

Alternative Symbols: ADA1

Protein Name: Adenosine deaminase

Molekulargewicht: 41kDa

Gen-ID: 100

NCBI Accession: NP_000013

UniProt: P00813

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Ribonucleoside Biosynthetic Process