HIST2H2AA3 Antikörper (Middle Region)

Produktnummer ABIN2784541

Produktdetails anti-HIST2H2AA3 Antikörper

Target: HIST2H2AA3 (Histone Cluster 2, H2aa3 (HIST2H2AA3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HIST2H2AA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PRHLQLAIRN DEELNKLLGK VTIAQGGVLP NIQAVLLPKK TESHHKAKGK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HIST2H2AA3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HIST2H2AA3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 130 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HIST2H2AA3

Target: HIST2H2AA3 (Histone Cluster 2, H2aa3 (HIST2H2AA3))

Andere Bezeichnung: HIST2H2AA3 (HIST2H2AA3 Produkte)

Synonyme: H2A antikoerper, H2A.2 antikoerper, H2A/O antikoerper, H2A/q antikoerper, H2AFO antikoerper, H2a-615 antikoerper, HIST2H2AA antikoerper, Hist2h2aa antikoerper, Hist2h2aa1 antikoerper, histone cluster 2 H2A family member a3 antikoerper, histone cluster 2 H2A family member A3 antikoerper, HIST2H2AA3 antikoerper, Hist2h2aa3 antikoerper

Hintergrund: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. HIST2H2AA3 is a member of the histone H2A family.Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated, this record represents the centromeric copy. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: H2A, H2A.2, H2A/O, H2A/q, H2AFO, H2a-615, HIST2H2AA
Protein Interaction Partner: USP21, DNAJC2, USP16, AURKB, UBC, WWOX, BAP1, SUZ12, RNF2, HCVgp1, PRMT6, IL33, APP, NOC2L, MEN1, SUMO2, RNF20, MSL2, BMI1, RNF168, HDAC1, PARP1, SRRM1, G3BP1, UBE2H, RCC1, TBL1X,
Protein Size: 130

Molekulargewicht: 14 kDa

Gen-ID: 8337

NCBI Accession: NM_003516, NP_003507

UniProt: Q7L7L0

Pathways: Telomere Maintenance