HIST2H2AC Antikörper (Middle Region)

Produktnummer ABIN2784540

Produktdetails anti-HIST2H2AC Antikörper

Target: HIST2H2AC (Histone Cluster 2, H2ac (HIST2H2AC))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Schwein, Kaninchen, Rind (Kuh), Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HIST2H2AC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: IPRHLQLAIR NDEELNKLLG KVTIAQGGVL PNIQAVLLPK KTESHKAKSK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HIST2H2AC. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HIST2H2AC

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 129 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HIST2H2AC

Target: HIST2H2AC (Histone Cluster 2, H2ac (HIST2H2AC))

Andere Bezeichnung: HIST2H2AC (HIST2H2AC Produkte)

Synonyme: HIST2H2AC antikoerper, H2A antikoerper, H2A-GL101 antikoerper, H2A/q antikoerper, H2AFQ antikoerper, H2a-613b antikoerper, RGD1560965 antikoerper, histone cluster 1, H2A, IV antikoerper, histone cluster 2 H2A family member c antikoerper, histone cluster 2, H2ac antikoerper, HIST1H2A4 antikoerper, HIST2H2AC antikoerper, Hist2h2ac antikoerper

Hintergrund: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. HIST2H2AC is a member of the histone H2A family.Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: H2A, H2A-GL101, H2A/q, H2AFQ, MGC74460
Protein Interaction Partner: BAP1, UBC, RNF2, INO80, UIMC1, RAD6, HDAC2, USP16, AURKB, NEDD8, CUL4A, USP15, SART3, HIST2H2BE, POLR2C, RNF168, HCVgp1, PRAME, RNF8, CRP, CENPA, HIST1H3B, EP300, KAT2A, BRCA1, BARD1, RBBP7, RBBP4, HAT1, ATXN7L3, USP22, MECP2, CHFR, DDB2, HIST1H4A, HIST1H
Protein Size: 129

Molekulargewicht: 14 kDa

Gen-ID: 8338

NCBI Accession: NM_003517, NP_003508

UniProt: Q16777