PPIA Antikörper (N-Term)

Produktnummer ABIN2784531

Dieses Anti-PPIA-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PPIA in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Kaninchen, Schaf und Saccharomyces cerevisiae.

Kurzübersicht für PPIA Antikörper (N-Term) (ABIN2784531)

Target: PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Kaninchen, Schaf, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPIA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PPIA Antikörper

Bindungsspezifität: N-Term

Sequenz: FRALSTGEKG FGYKGSCFHR IIPGFMCQGG DFTRHNGTGG KSIYGEKFED

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PPIA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PPIA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 165 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PPIA

Target: PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))

Andere Bezeichnung: PPIA

Hintergrund: PPIA is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. PPIA is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CYPA, CYPH, MGC117158, MGC12404, MGC23397
Protein Interaction Partner: LNX1, HUWE1, UBC, TCF4, FUS, gag, MDM2, RPL23A, SRPK2, SRPK1, ESR1, UBD, TERT, RAD52, VCAM1, ITGA4, FN1, HCVgp1, LIG4, PAXIP1, RB1, APP, CPLX1, SNX3, TAGLN2, SOD1, RPA2, RAD23B, PTMA, IGBP1, ENO1, AKT1, USP4, CDK2, COPS5, CUL1, CUL3, CUL4B, NEDD8, CD99, C
Protein Size: 165

Molekulargewicht: 18 kDa

Gen-ID: 5478

NCBI Accession: NM_021130, NP_066953

UniProt: P62937