PPIA Antikörper (Middle Region)

Produktnummer ABIN2784530

Der Kaninchen Polyklonal anti-PPIA Antikörper (ABIN2784530) detektiert spezifisch PPIA in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Kaninchen und Schaf.

Kurzübersicht für PPIA Antikörper (Middle Region) (ABIN2784530)

Target: PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Kaninchen, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPIA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-PPIA Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: PPIA Antibody - middle region

Sequenz: TAKTEWLDGK HVVFGKVKEG MNIVEAMERF GSRNGKTSKK ITIADCGQLE

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PPIA. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PPIA

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51352-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu PPIA

Target: PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))

Andere Bezeichnung: PPIA

Hintergrund:

Background Information: PPIA is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. PPIA is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a cyclosporin binding-protein. It may play a role in cyclosporin A-mediated immunosuppression. This protein can interact with several HIV proteins including p55 gag, Vpr, and capsid protein. It has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. Three alternatively spliced transcript variants encoding two distinct isoforms have been observed.

Gene Name: Peptidylprolyl isomerase A (cyclophilin A)

Alternative Symbols: CYPA, CYPH, HEL-S-69p

Protein Name: Peptidyl-prolyl cis-trans isomerase A

Molekulargewicht: 18kDa

Gen-ID: 5478

NCBI Accession: NP_066953

UniProt: P62937