Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

PPIA Antikörper (Middle Region)

Dieses Anti-PPIA-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PPIA in WB und IHC. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Kaninchen und Schaf.
Produktnummer ABIN2784530

Kurzübersicht für PPIA Antikörper (Middle Region) (ABIN2784530)

Target

Alle PPIA Antikörper anzeigen
PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))

Reaktivität

  • 111
  • 70
  • 66
  • 14
  • 9
  • 8
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte, Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Kaninchen, Schaf

Wirt

  • 135
  • 35
  • 3
  • 1
Kaninchen

Klonalität

  • 122
  • 52
Polyklonal

Konjugat

  • 92
  • 27
  • 19
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser PPIA Antikörper ist unkonjugiert

Applikation

  • 136
  • 87
  • 68
  • 43
  • 30
  • 26
  • 16
  • 13
  • 13
  • 10
  • 10
  • 4
  • 3
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 23
    • 20
    • 16
    • 16
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Sequenz

    TAKTEWLDGK HVVFGKVKEG MNIVEAMERF GSRNGKTSKK ITIADCGQLE

    Homologie

    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 100%

    Produktmerkmale

    This is a rabbit polyclonal antibody against PPIA. It was validated on Western Blot and immunohistochemistry.

    Aufreinigung

    Protein A purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the middle region of human PPIA
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 165 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))

    Andere Bezeichnung

    PPIA

    Hintergrund

    PPIA is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. PPIA is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a cyclosporin binding-protein. It may play a role in cyclosporin A-mediated immunosuppression. This protein can interact with several HIV proteins including p55 gag, Vpr, and capsid protein. It has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. Three alternatively spliced transcript variants encoding two distinct isoforms have been observed.
    Alias Symbols: CYPA, CYPH, MGC117158, MGC12404, MGC23397
    Protein Interaction Partner: LNX1, HUWE1, UBC, TCF4, FUS, gag, MDM2, RPL23A, SRPK2, SRPK1, ESR1, UBD, TERT, RAD52, VCAM1, ITGA4, FN1, HCVgp1, LIG4, PAXIP1, RB1, APP, CPLX1, SNX3, TAGLN2, SOD1, RPA2, RAD23B, PTMA, IGBP1, ENO1, AKT1, USP4, CDK2, COPS5, CUL1, CUL3, CUL4B, NEDD8, CD99, C
    Protein Size: 165

    Molekulargewicht

    18 kDa

    Gen-ID

    5478

    NCBI Accession

    NM_021130, NP_066953

    UniProt

    P62937
Sie sind hier:
Chat with us!