Der Kaninchen Polyklonal anti-PEG10 Antikörper (ABIN2784509) detektiert spezifisch PEG10 in WB.
Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Kaninchen, Rind (Kuh), Pferd, Hund und Meerschweinchen.
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeat freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target
PEG10
(Paternally Expressed 10 (PEG10))
Andere Bezeichnung
PEG10
Hintergrund
This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Alias Symbols: EDR, HB-1, MEF3L, Mar2, Mart2, RGAG3 Protein Interaction Partner: SIAH1, FAM127C, LDOC1, CALCOCO2, FAM127A, UBC, MAPT, HNRNPUL1, HNRNPH1, BAG1, TGFBR2, TGFBR1, BMPR1B, BMPR1A, ACVRL1, ACVR2B, ACVR2A, ACVR1B, ACVR1, RNF2, ZNF512B, RNF181, HMGCS1, TOLLIP, IRF4, SIAH2, Protein Size: 708