P2RY1 Antikörper (N-Term)

Produktnummer ABIN2784500

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-P2RY1 Antikörper wird verwendet zum Nachweis von P2RY1 in Proben von Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Kaninchen, Pferd, Hund und Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für P2RY1 Antikörper (N-Term) (ABIN2784500)

Target: P2RY1 (Purinergic Receptor P2Y, G-Protein Coupled, 1 (P2RY1))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Kaninchen, Pferd, Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser P2RY1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-P2RY1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: P2RY1 Antibody - N-terminal region

Sequenz: VAIWMFVFHM KPWSGISVYM FNLALADFLY VLTLPALIFY YFNKTDWIFG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against P2RY1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human P2RY1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51293-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-P2RY1 Antikörper (ABIN2784500)

Dilip, Ishii, Imada, Wada-Kiyama, Kiyama, Miyachi, Kaneda: "Distribution and development of P2Y1-purinoceptors in the mouse retina." in: Journal of molecular histology, Vol. 44, Issue 6, pp. 639-44, (2013) (PubMed).

Details zu P2RY1

Target: P2RY1 (Purinergic Receptor P2Y, G-Protein Coupled, 1 (P2RY1))

Andere Bezeichnung: P2RY1

Hintergrund:

Background Information: The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008].

Gene Name: Purinergic receptor P2Y, G-protein coupled, 1

Alternative Symbols: P2Y1, SARCC

Protein Name: P2Y purinoceptor 1

Molekulargewicht: 42kDa

Gen-ID: 5028

NCBI Accession: NP_002554

UniProt: P47900

Pathways: Regulation of Carbohydrate Metabolic Process, Feeding Behaviour