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P2RY1 Antikörper (N-Term)

Der Kaninchen Polyklonal Anti-P2RY1-Antikörper wurde für WB validiert. Er ist geeignet, P2RY1 in Proben von Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Kaninchen, Pferd, Hund und Zebrafisch (Danio rerio) zu detektieren. Es ist 1 Publikation verfügbar.
Produktnummer ABIN2784500

Kurzübersicht für P2RY1 Antikörper (N-Term) (ABIN2784500)

Target

Alle P2RY1 Antikörper anzeigen
P2RY1 (Purinergic Receptor P2Y, G-Protein Coupled, 1 (P2RY1))

Reaktivität

  • 51
  • 18
  • 16
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Kaninchen, Pferd, Hund, Zebrafisch (Danio rerio)

Wirt

  • 43
  • 7
  • 1
Kaninchen

Klonalität

  • 47
  • 4
Polyklonal

Konjugat

  • 32
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser P2RY1 Antikörper ist unkonjugiert

Applikation

  • 29
  • 25
  • 19
  • 7
  • 6
  • 5
  • 4
  • 4
  • 4
  • 2
Western Blotting (WB)
  • Bindungsspezifität

    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    VAIWMFVFHM KPWSGISVYM FNLALADFLY VLTLPALIFY YFNKTDWIFG

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

    Produktmerkmale

    This is a rabbit polyclonal antibody against P2RY1. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human P2RY1
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 373 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Dilip, Ishii, Imada, Wada-Kiyama, Kiyama, Miyachi, Kaneda: "Distribution and development of P2Y1-purinoceptors in the mouse retina." in: Journal of molecular histology, Vol. 44, Issue 6, pp. 639-44, (2013) (PubMed).

  • Target

    P2RY1 (Purinergic Receptor P2Y, G-Protein Coupled, 1 (P2RY1))

    Andere Bezeichnung

    P2RY1

    Hintergrund

    The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008].
    Alias Symbols: P2y1, P2Y1
    Protein Interaction Partner: SLC9A3R2, SLC9A3R1, ADORA1,
    Protein Size: 373

    Molekulargewicht

    42 kDa

    Gen-ID

    5028

    NCBI Accession

    NM_002563, NP_002554

    UniProt

    P47900

    Pathways

    Regulation of Carbohydrate Metabolic Process, Feeding Behaviour
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