TNNT3 Antikörper (N-Term)
Kurzübersicht für TNNT3 Antikörper (N-Term) (ABIN2784497)
Target
Alle TNNT3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- PRPKLTAPKI PEGEKVDFDD IQKKRQNKDL MELQALIDSH FEARKKEEEE
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Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against TNNT3. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human TNNT3
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 250 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Calpain inhibition rescues troponin T3 fragmentation, increases Cav1.1, and enhances skeletal muscle force in aging sedentary mice." in: Aging cell, Vol. 15, Issue 3, pp. 488-98, (2016) (PubMed).
: "Nonmyofilament-associated troponin T3 nuclear and nucleolar localization sequence and leucine zipper domain mediate muscle cell apoptosis." in: Cytoskeleton (Hoboken, N.J.), Vol. 70, Issue 3, pp. 134-47, (2013) (PubMed).
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Calpain inhibition rescues troponin T3 fragmentation, increases Cav1.1, and enhances skeletal muscle force in aging sedentary mice." in: Aging cell, Vol. 15, Issue 3, pp. 488-98, (2016) (PubMed).
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- TNNT3 (Fast Skeletal Troponin T (TNNT3))
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Andere Bezeichnung
- TNNT3
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Hintergrund
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Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Alias Symbols: AMCD2B, DA2B, DKFZp779M2348, FSSV, TNTF
Protein Interaction Partner: TNNC1, TPM1, TNNI2, TNNC2, TNNT3, NUDT3, TSG101, TRIM63, SNUPN, HAP1,
Protein Size: 250 -
Molekulargewicht
- 30 kDa
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Gen-ID
- 7140
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NCBI Accession
- NM_001042780, NP_001036245
Target
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