PHC2 Antikörper (N-Term)

Produktnummer ABIN2784482

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PHC2 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für PHC2 Antikörper (N-Term) (ABIN2784482)

Target: PHC2 (PhC2) (Polyhomeotic Homolog 2 (Drosophila) (PhC2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PHC2 Antikörper

Bindungsspezifität: N-Term

Sequenz: GGSGRPTGPQ ISVYSGIPDR QTVQVIQQAL HRQPSTAAQY LQQMYAAQQQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PHC2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PHC2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 858 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PHC2

Target: PHC2 (PhC2) (Polyhomeotic Homolog 2 (Drosophila) (PhC2))

Andere Bezeichnung: PHC2

Hintergrund: In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: EDR2, HPH2, MGC163502, PH2
Protein Interaction Partner: FAM74A4, FAM74A1, FAM13C, FAM124A, MAGEB6, ZMAT2, ZNF417, MAB21L3, SSX2IP, TRIM41, ZGPAT, L3MBTL3, PCGF5, SPATC1L, FAM161A, ENKD1, KBTBD7, SYT16, THAP7, AEN, CARD9, CBX8, C1orf109, SFMBT1, PRPF31, PPP1R16B, KAT5, PCGF3, RWDD2B, ZBTB24, MORF4L2, RBM39, AP1
Protein Size: 858

Molekulargewicht: 91 kDa

Gen-ID: 1912

NCBI Accession: NM_198040, NP_932157

UniProt: Q8IXK0