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PHF6 Antikörper (N-Term)

This anti-PHF6 antibody (ABIN2784476) is a Rabbit Polyclonal antibody detecting PHF6 in WB. Suitable for Human, Mouse, Dog, Cow, Rat, Horse, Rabbit, Pig, Guinea Pig.
Produktnummer ABIN2784476

Quick Overview for PHF6 Antikörper (N-Term) (ABIN2784476)

Target

Alle PHF6 Antikörper anzeigen
PHF6 (PHD Finger Protein 6 (PHF6))

Reaktivität

  • 36
  • 8
  • 7
  • 6
  • 6
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
Human, Maus, Hund, Rind (Kuh), Ratte, Pferd, Kaninchen, Schwein, Meerschweinchen

Wirt

  • 34
  • 2
Kaninchen

Klonalität

  • 35
  • 1
Polyklonal

Konjugat

  • 26
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser PHF6 Antikörper ist unkonjugiert

Applikation

  • 24
  • 10
  • 7
  • 7
  • 7
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    VGQNHSEDGA PALLTTAPPP GLQPGAGGTP GGPGGGGAPP RYATLEHPFH

    Homologie

    Cow: 93%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 100%

    Produktmerkmale

    This is a rabbit polyclonal antibody against PHF6. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Protein A purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human PHF6
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 365 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    PHF6 (PHD Finger Protein 6 (PHF6))

    Andere Bezeichnung

    PHF6

    Hintergrund

    PHF6 is a member of the plant homeodomain (PHD)-like finger (PHF) family. PHF6 is a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation that localizes to the nucleolus. Mutations affecting the coding region of its gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by mental retardation, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears.This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by mental retardation, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
    Alias Symbols: BORJ, MGC14797, BFLS, CENP-31
    Protein Interaction Partner: UBC, SUMO1, NEDD8, BMI1, HECW2, CAND1, CUL3, HDGF,
    Protein Size: 365

    Molekulargewicht

    41 kDa

    Gen-ID

    84295

    NCBI Accession

    NM_032458, NP_115834

    UniProt

    Q8IWS0
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