PHF6 Antikörper (C-Term)

Produktnummer ABIN2784475

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PHF6 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PHF6 Antikörper (C-Term) (ABIN2784475)

Target: PHF6 (PHD Finger Protein 6 (PHF6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHF6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PHF6 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: PHF6 Antibody - C-terminal region

Sequenz: DFDIKTVLQE IKRGKRMVCS FYICYATLHL ICCFKFRVHP KFIQSSENLK

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PHF6. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PHF6

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51236-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu PHF6

Target: PHF6 (PHD Finger Protein 6 (PHF6))

Andere Bezeichnung: PHF6

Hintergrund:

Background Information: PHF6 is a member of the plant homeodomain (PHD)-like finger (PHF) family. PHF6 is a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of its gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS).This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by mental retardation, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene Name: PHD finger protein 6

Alternative Symbols: BFLS, BORJ, CENP-31

Protein Name: PHD finger protein 6

Molekulargewicht: 35kDa

Gen-ID: 84295

NCBI Accession: NP_115711

UniProt: Q5JRC7