Frataxin Antikörper (C-Term)

Produktnummer ABIN2784465

Der Kaninchen Polyklonal anti-Frataxin Antikörper wird verwendet zum Nachweis von Frataxin in Proben von Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Hund, Meerschweinchen, Saccharomyces cerevisiae und Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für Frataxin Antikörper (C-Term) (ABIN2784465)

Target: Frataxin (FXN)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Hund, Meerschweinchen, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Frataxin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Frataxin Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Fxn Antibody - C-terminal region

Sequenz: EFFEDLADKP YTLKDYDVSF GDGVLTIKLG GDLGTYVINK QTPNKQIWLS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against Fxn. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Rat

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51215-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Frataxin

Target: Frataxin (FXN)

Andere Bezeichnung: Fxn

Hintergrund:

Background Information: Fxn promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. It may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+, the oligomeric form but not the monomeric form has in vitro ferroxidase activity. It may be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Fxn modulates the RNA-binding activity of ACO1.

Gene Name: Frataxin

Alternative Symbols: RGD1565754

Protein Name: Frataxin, mitochondrial

Molekulargewicht: 23kDa

Gen-ID: 499335

NCBI Accession: XP_001078791

UniProt: D3ZYW7

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size