DLG4 Antikörper (Middle Region)

Produktnummer ABIN2784457

Dieses Anti-DLG4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DLG4 in WB. Geeignet für Ratte, Human, Maus, Rind (Kuh), Kaninchen, Zebrafisch (Danio rerio), Hund, Pferd und Meerschweinchen.

Kurzübersicht für DLG4 Antikörper (Middle Region) (ABIN2784457)

Target: DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

Reaktivität: Ratte, Human, Maus, Rind (Kuh), Kaninchen, Zebrafisch (Danio rerio), Hund, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLG4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DLG4 Antikörper

Bindungsspezifität: Middle Region

Sequenz: AAHLHPIAIF IRPRSLENVL EINKRITEEQ ARKAFDRATK LEQEFTECFS

Homologie: Cow: 100%, Dog: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against DLG4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DLG4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 767 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DLG4

Target: DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

Andere Bezeichnung: DLG4

Hintergrund: This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: PSD95, SAP90, SAP-90
Protein Interaction Partner: SPRR2A, UBC, BAI1, Mbp, MED28, RAD23A, MDM2, PCDH10, MAP1A, KCNA3, KCNA4, GRIN2B, GRIK2, ADRB1, CUL3, KCNA5, GRIN2A, ERBB4, KHDRBS1, ELAVL1, LRFN1, TANC1, GRASP, DLGAP4, SYNGAP1, GRIN1, LPHN1, ARHGAP32, GNG13, SIPA1L1, ASIC3, NDOR1, SEMA4G, SEMA4B, LIN7B,
Protein Size: 767

Molekulargewicht: 85 kDa

Gen-ID: 1742

NCBI Accession: NM_001365, NP_001356

UniProt: P78352

Pathways: Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity