NAGS Antikörper (C-Term)

Produktnummer ABIN311403

Dieser Anti-NAGS Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von NAGS in WB. Geeignet für Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Schwein, Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für NAGS Antikörper (C-Term) (ABIN311403)

Target: NAGS (N-Acetylglutamate Synthase (NAGS))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Schwein, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NAGS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NAGS Antikörper

Bindungsspezifität: C-Term

Sequenz: YLDKFVVSSS RQGQGSGQML WECLRRDLQT LFWRSRVTNP INPWYFKHSD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against NAGS. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NAGS

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 534 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NAGS

Target: NAGS (N-Acetylglutamate Synthase (NAGS))

Andere Bezeichnung: NAGS

Hintergrund: NAGS is a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.
Alias Symbols: AGAS, ARGA, MGC133025
Protein Interaction Partner: TMEM39B,
Protein Size: 534

Molekulargewicht: 58 kDa

Gen-ID: 162417

NCBI Accession: NM_153006, NP_694551

UniProt: Q8N159