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FHIT Antikörper (Middle Region)

FHIT Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Hund, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2784442
  • Target Alle FHIT Antikörper anzeigen
    FHIT (Fragile Histidine Triad (FHIT))
    Bindungsspezifität
    • 17
    • 15
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    Human, Maus, Ratte, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Hund, Kaninchen
    Wirt
    • 73
    • 10
    Kaninchen
    Klonalität
    • 73
    • 10
    Polyklonal
    Konjugat
    • 34
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser FHIT Antikörper ist unkonjugiert
    Applikation
    • 40
    • 34
    • 26
    • 26
    • 14
    • 10
    • 8
    • 6
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    VHVLPRKAGD FHRNDSIYEE LQKHDKEDFP ASWRSEEEMA AEAAALRVYF
    Homologie
    Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 79%, Zebrafish: 86%
    Produktmerkmale
    This is a rabbit polyclonal antibody against FHIT. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human FHIT
    Top Product
    Discover our top product FHIT Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 147 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    FHIT (Fragile Histidine Triad (FHIT))
    Andere Bezeichnung
    FHIT (FHIT Produkte)
    Synonyme
    AP3Aase antikoerper, FRA3B antikoerper, FHIT antikoerper, zgc:73176 antikoerper, AW045638 antikoerper, Fra14A2 antikoerper, LOC100223655 antikoerper, fragile histidine triad antikoerper, fragile histidine triad gene antikoerper, fragile histidine triad protein antikoerper, fragile histidine triad L homeolog antikoerper, FHIT antikoerper, Fhit antikoerper, fhit antikoerper, PY07476 antikoerper, fhit.L antikoerper
    Hintergrund
    This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene.
    Alias Symbols: AP3Aase, FRA3B
    Protein Interaction Partner: FHIT, REL, MDM2, UBC, RAB40B, TRIM23, LEF1, CTNNB1, UBE2I, SRC, GSN, HSPD1, FDXR,
    Protein Size: 147
    Molekulargewicht
    17 kDa
    Gen-ID
    2272
    NCBI Accession
    NM_002012, NP_002003
    UniProt
    P49789
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