PYHIN1 Antikörper (N-Term)

Produktnummer ABIN2784367

Der Kaninchen Polyklonal anti-PYHIN1 Antikörper wird verwendet zum Nachweis von PYHIN1 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für PYHIN1 Antikörper (N-Term) (ABIN2784367)

Target: PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PYHIN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PYHIN1 Antikörper

Bindungsspezifität: N-Term

Sequenz: ANNYKKIVLL KGLEVINDYH FRIVKSLLSN DLKLNPKMKE EYDKIQIADL

Homologie: Cow: 91%, Dog: 91%, Horse: 91%, Human: 100%, Mouse: 100%, Pig: 85%, Rabbit: 93%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against PYHIN1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PYHIN1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 492 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PYHIN1

Target: PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))

Andere Bezeichnung: PYHIN1

Hintergrund: PYHIN1 belongs to the HIN-200 family. This protein is major mediator of the tumor suppressor activity of IFN in breast cancer cells. It promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization, and HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells.
Alias Symbols: IFIX, MGC23885, RP11-520H16.1
Protein Interaction Partner: MDM2,
Protein Size: 492

Molekulargewicht: 55 kDa

Gen-ID: 149628

NCBI Accession: NM_152501, NP_689714

UniProt: Q6K0P9