GTF2A1L Antikörper (C-Term)

Produktnummer ABIN2784347

Der Kaninchen Polyklonal anti-GTF2A1L Antikörper wird verwendet zum Nachweis von GTF2A1L in Proben von Human, Hund, Pferd, Ratte und Maus. Er wurde validiert für WB.

Kurzübersicht für GTF2A1L Antikörper (C-Term) (ABIN2784347)

Target: GTF2A1L (General Transcription Factor IIA, 1-Like (GTF2A1L))

Reaktivität: Human, Hund, Pferd, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GTF2A1L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GTF2A1L Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: GTF2A1L Antibody - C-terminal region

Sequenz: RVTDDDIGEI IQVDGSGDTS SNEEIGSTRD ADENEFLGNI DGGDLKVPEE

Homologie: Dog: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against GTF2A1L. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GTF2A1L

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8101417

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu GTF2A1L

Target: GTF2A1L (General Transcription Factor IIA, 1-Like (GTF2A1L))

Andere Bezeichnung: GTF2A1L

Hintergrund:

Background Information: The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology.The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

Gene Name: General transcription factor IIA, 1-like

Alternative Symbols: ALF

Protein Name: TFIIA-alpha and beta-like factor

Molekulargewicht: 52kDa

Gen-ID: 11036

NCBI Accession: NP_006863

UniProt: Q9UNN4