DCP1B Antikörper (N-Term)

Produktnummer ABIN2784340

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch DCP1B in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd und Schwein.

Kurzübersicht für DCP1B Antikörper (N-Term) (ABIN2784340)

Target: DCP1B (DCP1 Decapping Enzyme Homolog B (DCP1B))

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DCP1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DCP1B Antikörper

Bindungsspezifität: N-Term

Sequenz: TLDPEPQHLS LTALFGKQDK ATCQETVEPP QTLHQQQQQQ QQQQEKLPIR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against DCP1B. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DCP1B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 617 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DCP1B

Target: DCP1B (DCP1 Decapping Enzyme Homolog B (DCP1B))

Andere Bezeichnung: DCP1B

Hintergrund: DCP1B may play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. It may remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP.DCP1B is a core component of the mRNA decapping complex, a key factor in the regulation of mRNA decay (Lykke-Andersen, 2002 [PubMed 12417715]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-844 AY146652.1 1-844 845-2079 BC015368.2 379-1613 2080-2105 AW204088.1 3-28 c
Alias Symbols: DCP1, hDcp1b
Protein Interaction Partner: EDC3, ZFP36, UBC, E2F7, DCP1A, EDC4, PPM1A, DDX6, DCP2, KANK2, PNRC1, BAG4, EXOSC6, XRN1, LSM8, UPF2, SMAD4, HSPA1L, USP4,
Protein Size: 617

Molekulargewicht: 68 kDa

Gen-ID: 196513

NCBI Accession: NM_152640, NP_689853

UniProt: Q8IZD4