TRAPPC2 Antikörper (Middle Region)

Produktnummer ABIN2784240

Der Kaninchen Polyklonal anti-TRAPPC2 Antikörper wird verwendet zum Nachweis von TRAPPC2 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für TRAPPC2 Antikörper (Middle Region) (ABIN2784240)

Target: TRAPPC2 (Trafficking Protein Particle Complex 2 (TRAPPC2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRAPPC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TRAPPC2 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: TRAPPC2 Antibody - middle region

Sequenz: RQEDGIKNFF TDVYDLYIKF SMNPFYEPNS PIRSSAFDRK VQFLGKKHLL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TRAPPC2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TRAPPC2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50568-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu TRAPPC2

Target: TRAPPC2 (Trafficking Protein Particle Complex 2 (TRAPPC2))

Andere Bezeichnung: TRAPPC2

Hintergrund:

Targeted Subunit: 2

Background Information: TRAPPC2 prevents MBP1-mediated transcriptional repression and antagonizes MBP1-mediated cell death. TRAPPC2 may play a role in vesicular transport from endoplasmic reticulum to Golgi.The protein encoded by this gene is thought to be part of a large multisubunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, the encoded protein can bind MBP1 and block its transcriptional repression capability. Mutations in this gene are a cause of spondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogene of this gene is located on chromosome 19, and other pseuodogenes are found on chromosomes 8 and Y. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been found for this gene.

Gene Name: Trafficking protein particle complex 2

Alternative Symbols: SEDL, SEDT, MIP2A, TRS20, ZNF547L, hYP38334, TRAPPC2P1

Molekulargewicht: 16kDa

Gen-ID: 6399

NCBI Accession: NP_055378

UniProt: O14582