Ataxin 3 Antikörper (N-Term)

Produktnummer ABIN2784210

Der Kaninchen Polyklonal Anti-Ataxin 3-Antikörper wurde für WB validiert. Er ist geeignet, Ataxin 3 in Proben von Human, Maus, Ratte, Rind (Kuh), Schaf, Pferd, Kaninchen, Meerschweinchen, Hund und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für Ataxin 3 Antikörper (N-Term) (ABIN2784210)

Target: Ataxin 3 (ATXN3)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schaf, Pferd, Kaninchen, Meerschweinchen, Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ataxin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Ataxin 3 Antikörper

Bindungsspezifität: N-Term

Sequenz: SIAHQLDEEE RMRMAEGGVT SEDYRTFLQQ PSGNMDDSGF FSIQVISNAL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against ATXN3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ATXN3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 361 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Ataxin 3

Target: Ataxin 3 (ATXN3)

Andere Bezeichnung: ATXN3

Hintergrund: Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: AT3, ATX3, JOS, MJD, MJD1, SCA3
Protein Interaction Partner: UBC, NEDD8, ATXN3, TRIM63, SQSTM1, VCP, ITCH, PARK2, MGRN1, TUBB, HDAC6, TUBA1A, ELC1, ELA1, SYVN1, BAG3, BCL2L1, STUB1, SUMO1, APP, RFFL, TRIM55, SPRTN, PJA1, TRIM54, USP21, UBE2L3, ARHGDIA, ASIC1, RAD23B, RAD23A, ARHGAP19, C16orf70, TEX11, PICK1, GSK3B,
Protein Size: 361

Molekulargewicht: 41 kDa

Gen-ID: 4287

NCBI Accession: NM_004993, NP_004984

UniProt: P54252