ANKH Antikörper (N-Term)

Produktnummer ABIN2784109

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ANKH in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Meerschweinchen, Kaninchen, Rind (Kuh), Pferd und Zebrafisch (Danio rerio).

Kurzübersicht für ANKH Antikörper (N-Term) (ABIN2784109)

Target: ANKH (Ankylosis, Progressive Homolog (Mouse) (ANKH))

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Kaninchen, Rind (Kuh), Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANKH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ANKH Antikörper

Bindungsspezifität: N-Term

Sequenz: SDLGYYIINK LHHVDESVGS KTRRAFLYLA AFPFMDAMAW THAGILLKHK

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ANKH. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ANKH

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 492 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ANKH

Target: ANKH (Ankylosis, Progressive Homolog (Mouse) (ANKH))

Andere Bezeichnung: ANKH

Hintergrund: ANKH regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.This gene encodes a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals. Mutations in this gene have been associated with autosomal dominant craniometaphyseal dysplasia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ANK, CCAL2, CMDJ, CPPDD, FLJ27166, HANK, MANK
Protein Interaction Partner: UBC, RPSA, APOE,
Protein Size: 492

Molekulargewicht: 54 kDa

Gen-ID: 56172

NCBI Accession: NM_054027, NP_473368

UniProt: Q9HCJ1