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RFT1 Antikörper (N-Term)

RFT1 Reaktivität: Human, Hund, Maus, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2784093
  • Target Alle RFT1 Antikörper anzeigen
    RFT1 (RFT1 Homolog (RFT1))
    Bindungsspezifität
    • 8
    • 8
    • 7
    • 1
    • 1
    N-Term
    Reaktivität
    Human, Hund, Maus, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Ratte
    Wirt
    • 17
    • 1
    Kaninchen
    Klonalität
    • 18
    Polyklonal
    Konjugat
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser RFT1 Antikörper ist unkonjugiert
    Applikation
    • 17
    • 14
    • 13
    • 3
    • 1
    Western Blotting (WB)
    Sequenz
    GTQRDWSQTL NLLWLTVPLG VFWSLFLGWI WLQLLEVPDP NVVPHYATGV
    Homologie
    Cow: 92%, Dog: 100%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 85%, Rabbit: 92%, Rat: 92%
    Produktmerkmale
    This is a rabbit polyclonal antibody against RFT1. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human RFT1
    Top Product
    Discover our top product RFT1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 541 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    RFT1 (RFT1 Homolog (RFT1))
    Andere Bezeichnung
    RFT1 (RFT1 Produkte)
    Synonyme
    GB14370 antikoerper, CDG1N antikoerper, D930025H04 antikoerper, RGD1562654 antikoerper, protein RFT1 homolog antikoerper, RFT1 homolog antikoerper, LOC412489 antikoerper, LOC100453537 antikoerper, RFT1 antikoerper, rft1 antikoerper, LOC100633251 antikoerper, LOC100651701 antikoerper, Rft1 antikoerper
    Hintergrund
    N-glycosylation of proteins follows a highly conserved pathway that begins with the synthesis of a!!Man(5)GlcNAc(2)-dolichylpyrophosphate (PP-Dol) intermediate on the cytoplasmic side of the endoplasmic reticulum (ER) membrane followed by the translocation of Man(5)GlcNAc (2)-PP-Dol to the luminal side of the ER membrane. RFT1 is the flippase enzyme that catalyzes this translocation.N-glycosylation of proteins follows a highly conserved pathway that begins with the synthesis of a Man(5)GlcNAc(2)-dolichylpyrophosphate (PP-Dol) intermediate on the cytoplasmic side of the endoplasmic reticulum (ER) membrane followed by the translocation of Man(5)GlcNAc (2)-PP-Dol to the luminal side of the ER membrane. RFT1 is the flippase enzyme that catalyzes this translocation (Helenius et al., 2002 [PubMed 11807558]).[supplied by OMIM].
    Alias Symbols: CDG1N
    Protein Interaction Partner: PSMA3, UBC, NEDD4,
    Protein Size: 541
    Molekulargewicht
    60 kDa
    Gen-ID
    91869
    NCBI Accession
    NM_052859, NP_443091
    UniProt
    Q96AA3
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