RFT1 Antikörper (N-Term)

Produktnummer ABIN2784093

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch RFT1 in WB. Er zeigt eine Reaktivität gegenüber Human, Hund, Maus, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen und Ratte.

Kurzübersicht für RFT1 Antikörper (N-Term) (ABIN2784093)

Target: RFT1 (RFT1 Homolog (RFT1))

Reaktivität: Human, Hund, Maus, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RFT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RFT1 Antikörper

Bindungsspezifität: N-Term

Sequenz: GTQRDWSQTL NLLWLTVPLG VFWSLFLGWI WLQLLEVPDP NVVPHYATGV

Homologie: Cow: 92%, Dog: 100%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 85%, Rabbit: 92%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against RFT1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RFT1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 541 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RFT1

Target: RFT1 (RFT1 Homolog (RFT1))

Andere Bezeichnung: RFT1

Hintergrund: N-glycosylation of proteins follows a highly conserved pathway that begins with the synthesis of a!!Man(5)GlcNAc(2)-dolichylpyrophosphate (PP-Dol) intermediate on the cytoplasmic side of the endoplasmic reticulum (ER) membrane followed by the translocation of Man(5)GlcNAc (2)-PP-Dol to the luminal side of the ER membrane. RFT1 is the flippase enzyme that catalyzes this translocation.N-glycosylation of proteins follows a highly conserved pathway that begins with the synthesis of a Man(5)GlcNAc(2)-dolichylpyrophosphate (PP-Dol) intermediate on the cytoplasmic side of the endoplasmic reticulum (ER) membrane followed by the translocation of Man(5)GlcNAc (2)-PP-Dol to the luminal side of the ER membrane. RFT1 is the flippase enzyme that catalyzes this translocation (Helenius et al., 2002 [PubMed 11807558]).[supplied by OMIM].
Alias Symbols: CDG1N
Protein Interaction Partner: PSMA3, UBC, NEDD4,
Protein Size: 541

Molekulargewicht: 60 kDa

Gen-ID: 91869

NCBI Accession: NM_052859, NP_443091

UniProt: Q96AA3