BSCL2 Antikörper (C-Term)

Produktnummer ABIN2784048

Der Kaninchen Polyklonal anti-BSCL2 Antikörper (ABIN2784048) detektiert spezifisch BSCL2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen und Pferd.

Kurzübersicht für BSCL2 Antikörper (C-Term) (ABIN2784048)

Target: BSCL2 (Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BSCL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BSCL2 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: BSCL2 Antibody - C-terminal region

Sequenz: QEESTPQSDV TEDGESPEDP SGTEGQLSEE EKPDQQPLSG EEELEPEAS

Homologie: Cow: 86%, Dog: 86%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against BSCL2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human BSCL2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50102-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu BSCL2

Target: BSCL2 (Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2))

Andere Bezeichnung: BSCL2

Hintergrund:

Background Information: This gene encodes protein seipin, which is located in the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: Berardinelli-Seip congenital lipodystrophy 2 (seipin)

Alternative Symbols: HMN5, PELD, HMN5C, SPG17, GNG3LG

Protein Name: Seipin

Molekulargewicht: 44 kDa

Gen-ID: 26580

NCBI Accession: NP_001116427

UniProt: Q96G97