LIM2 Antikörper (N-Term)
Kurzübersicht für LIM2 Antikörper (N-Term) (ABIN503108)
Target
Alle LIM2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Verwendungszweck
- LIM2 Antibody - N-terminal region
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Sequenz
- GSFAHQGLWR YCLGNKCYLQ TDSIGEPPGQ GPGRAWGKSR ADLGAQGHLY
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Homologie
- Human: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against LIM2. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human LIM2
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49954-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Expressed sequence tag analysis of adult human lens for the NEIBank Project: over 2000 non-redundant transcripts, novel genes and splice variants." in: Molecular vision, Vol. 8, pp. 171-84, (2002) (PubMed).
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- LIM2 (Lens Intrinsic Membrane Protein 2, 19kDa (LIM2))
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Andere Bezeichnung
- LIM2
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Hintergrund
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Background Information: This gene encodes an eye lens-specific protein found at the junctions of lens fiber cells, where it may contribute to cell junctional organization. It acts as a receptor for calmodulin, and may play an important role in both lens development and cataractogenesis. Mutations in this gene have been associated with cataract formation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene Name: lens intrinsic membrane protein 2
Alternative Symbols: MP17, MP19, CTRCT19
Protein Name: lens fiber membrane intrinsic protein
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Molekulargewicht
- 24kDa
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Gen-ID
- 3982
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NCBI Accession
- NP_085915
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UniProt
- P55344
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Pathways
- Cell-Cell Junction Organization
Target
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