Plexin A2 Antikörper (N-Term)

Produktnummer ABIN2783972

Produktdetails anti-Plexin A2 Antikörper

Target: Plexin A2 (Plxna2)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Plexin A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SVASYVYNGY SVVFVGTKSG KLKKIRADGP PHGGVQYEMV SVLKDGSPIL

Homologie: Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against PLXNA2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PLXNA2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1894 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Plexin A2 Antikörper (ABIN2783972)

Budel, Shim, Feng, Zhao, Hisama, Strittmatter: "No association between schizophrenia and polymorphisms of the PlexinA2 gene in Chinese Han Trios." in: Schizophrenia research, Vol. 99, Issue 1-3, pp. 365-6, (2008) (PubMed).

Details zu Plexin A2

Target: Plexin A2 (Plxna2)

Andere Bezeichnung: PLXNA2 (Plxna2 Produkte)

Hintergrund: PLXNA2 is a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C. This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C.
Alias Symbols: FLJ11751, FLJ30634, KIAA0463, OCT, PLXN2
Protein Interaction Partner: CEMIP, FNBP4, UBAP2L, IFT80, HACE1, DHX37,
Protein Size: 1894

Molekulargewicht: 211 kDa

Gen-ID: 5362

NCBI Accession: NM_025179, NP_079455

UniProt: O75051