SRD5A3 Antikörper (N-Term)
Kurzübersicht für SRD5A3 Antikörper (N-Term) (ABIN2783928)
Target
Alle SRD5A3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- GLLPGCAIFQ DLIRYGKTKC GEPSRPAACR AFDVPKRYFS HFYIISVLWN
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Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 89%
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Produktmerkmale
- This is a rabbit polyclonal antibody against SRD5A3. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human SRD5A3
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 318 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Novel 5 alpha-steroid reductase (SRD5A3, type-3) is overexpressed in hormone-refractory prostate cancer." in: Cancer science, Vol. 99, Issue 1, pp. 81-6, (2007) (PubMed).
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: "Novel 5 alpha-steroid reductase (SRD5A3, type-3) is overexpressed in hormone-refractory prostate cancer." in: Cancer science, Vol. 99, Issue 1, pp. 81-6, (2007) (PubMed).
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- SRD5A3 (Steroid 5 alpha-Reductase 3 (SRD5A3))
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Andere Bezeichnung
- SRD5A3
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Hintergrund
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SRD5A3 belongs to the steroid 5-alpha reductase family and converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT).
Alias Symbols: FLJ13352, SRD5A2L, CDG1P, CDG1Q, KRIZI, SRD5A2L1
Protein Interaction Partner: NUDT15, ADK, DFG10,
Protein Size: 318 -
Molekulargewicht
- 36 kDa
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Gen-ID
- 79644
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NCBI Accession
- NM_024592, NP_078868
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UniProt
- Q9H8P0
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Pathways
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis
Target
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