GNPTAB Antikörper (N-Term)

Produktnummer ABIN2783922

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GNPTAB in WB. Es zeigt Reaktivität gegenüber Proben von Human, Rind (Kuh), Hund, Meerschweinchen, Pferd, Maus, Kaninchen, Ratte und Zebrafisch (Danio rerio).

Kurzübersicht für GNPTAB Antikörper (N-Term) (ABIN2783922)

Target: GNPTAB (N-Acetylglucosamine-1-Phosphate Transferase, alpha and beta Subunits (GNPTAB))

Reaktivität: Human, Rind (Kuh), Hund, Meerschweinchen, Pferd, Maus, Kaninchen, Ratte, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GNPTAB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GNPTAB Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: GNPTAB Antibody - N-terminal region

Sequenz: FQFGEVVLEW SRDQYHVLFD SYRDNIAGKS FQNRLCLPMP IDVVYTWVNG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GNPTAB. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GNPTAB

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49815-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu GNPTAB

Target: GNPTAB (N-Acetylglucosamine-1-Phosphate Transferase, alpha and beta Subunits (GNPTAB))

Andere Bezeichnung: GNPTAB

Hintergrund:

Targeted Subunit: s alpha/beta

Background Information: This gene encodes two of three subunit types of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase, a heterohexameric complex composed of two alpha, two beta, and two gamma subunits. The encoded protein is proteolytically cleaved at the Lys928-Asp929 bond to yield mature alpha and beta polypeptides while the gamma subunits are the product of a distinct gene (GeneID 84572). In the Golgi apparatus, the heterohexameric complex catalyzes the first step in the synthesis of mannose 6-phosphate recognition markers on certain oligosaccharides of newly synthesized lysosomal enzymes. These recognition markers are essential for appropriate trafficking of lysosomal enzymes. Mutations in this gene have been associated with both mucolipidosis II and mucolipidosis IIIA.

Gene Name: N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits

Alternative Symbols: ICD, GNPTA

Protein Name: N-acetylglucosamine-1-phosphotransferase subunits alpha/beta

Molekulargewicht: 143kDa

Gen-ID: 79158

NCBI Accession: NP_077288

UniProt: Q3T906